Mandatory | Alerts | Exclusionary | |
---|---|---|---|
Seizures | Focal cognitive (particularly déjà vu), sensory, or autonomic seizures | Generalized onset seizures | |
EEG | Generalized epileptiform abnormality | ||
Age at onset | |||
Development at onset | Intellectual impairment | ||
Neurological exam | Abnormal exam | ||
Imaging | Normal or hippocampal atrophy/ sclerosis | ||
Other | Family history of individuals with focal seizures that arise from the mesial temporal lobe | ||
Are MRI or ictal EEG required for diagnosis? An MRI is required for diagnosis An ictal EEG is not required for diagnosis |
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Syndrome without laboratory confirmation: in resource-limited regions, MRI is required to exclude other causes |
NOTE Alert criteria are absent in the vast majority of patients with the syndrome, but rarely can be seen. Their presence should result in caution in diagnosing the syndrome and consideration of other conditions