Hypoxic-ischemic structural brain abnormalities include loss of cerebral volume and scarring ('gliosis'). Acute seizures typically occur, maximal in the first 24 hours of the hypoxic-ischemic event. If epilepsy occurs following hypoxic-ischemic brain injury, there is typically a latent period after the hypoxic-ischemic event, followed by emergence of seizures.
Important hypoxic-ischemic associated structural brain abnormalities associated with epilepsy are presented in this section of EpilepsyDiagnosis.org: