ILAE Logo
Epilepsy Diagnosis Logo

SUBCORTICAL BAND HETEROTOPIA

GENETICS

PATTERN OF INHERITANCE

The pattern of inheritance depends on the gene abnormality. LIS1 is typically an acquired gene abnormality. DCX is inherited in an X-linked pattern.

KNOWN GENES
  • DCX - accounts for most cases of subcortical band heterotopia, with the heterotopia being bilateral, symmetric and anterior predominant, with a female predominance.
  • LIS1 - posterior predominant subcortical band heterotopia
FAMILY HISTORY

May be present (see above).

Feedback | Home | Contact Us | Privacy | Terms & Conditions of Use | Log In For Videos
Creative Commons License
This website is owned by the International League Against Epilepsy. Text on this website, last updated June 30, 2024,
is available under a Creative Commons Attribution-ShareAlike 4.0 International License,
EXCEPTING all videos and images, which remain copyrighted by the International League Against Epilepsy.